3,521 research outputs found

    Emotional and behavioral reaction to intrusive thoughts.

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    A self-report measure of the emotional and behavioral reactions to intrusive thoughts was developed. The article presents data that confirm the stability, reliability, and validity of the new seven-item measure. Emotional and behavioral reactions to intrusions emerged as separate factors on the Emotional and Behavioral Reactions to Intrusions Questionnaire (EBRIQ), a finding confirmed by an independent stress study. Test-retest reliability over 30 to 70 days was good. Expected relationships with other constructs were significant. Stronger negative responses to intrusions were associated with lower mindfulness scores and higher ratings of experiential avoidance, thought suppression, and intensity and frequency of craving. The EBRIQ will help explore differences in reactions to intrusive thoughts in clinical and nonclinical populations, and across different emotional and behavioral states. It will also be useful in assessing the effects of therapeutic approaches such as mindfulness

    XMM-Newton observation of the interacting galaxies NGC1512 and NGC1510

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    The galaxy NGC1512 is interacting with the smaller galaxy NGC1510 and shows a peculiar morphology, characterised by two extended arms immersed in an HI disc whose size is about four times larger than the optical diameter of NGC1512. For the first time we performed a deep X-ray observation of the galaxies NGC1512 and NGC1510 with XMM-Newton to gain information on the population of X-ray sources and diffuse emission in a system of interacting galaxies. We identified and classified the sources detected in the XMM-Newton field of view by means of spectral analysis, hardness-ratios calculated with a Bayesian method, X-ray variability, and cross-correlations with catalogues in optical, infrared, and radio wavelengths. We also made use of archival Swift (X-ray) and Australia Telescope Compact Array (radio) data to better constrain the nature of the sources detected with XMM-Newton. We detected 106 sources in the energy range of 0.2-12 keV, out of which 15 are located within the D_25 regions of NGC1512 and NGC1510 and at least six sources coincide with the extended arms. We identified and classified six background objects and six foreground stars. We discussed the nature of a source within the D_25 ellipse of NGC1512, whose properties indicate a quasi-stellar object or an intermediate ultra-luminous X-ray source. Taking into account the contribution of low-mass X-ray binaries and active galactic nuclei, the number of high-mass X-ray binaries detected within the D_25 region of NGC1512 is consistent with the star formation rate obtained in previous works based on radio, infrared optical, and UV wavelengths. We detected diffuse X-ray emission from the interior region of NGC1512 with a plasma temperature of kT=0.68(0.31-0.87) keV and a 0.3-10 keV X-ray luminosity of 1.3E38 erg/s, after correcting for unresolved discrete sources.Comment: Accepted for publication in Astronomy and Astrophysics. 20 pages. Appendix B will be published electronically onl

    Fully automated segmentation and tracking of the intima media thickness in ultrasound video sequences of the common carotid artery

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    Abstract—The robust identification and measurement of the intima media thickness (IMT) has a high clinical relevance because it represents one of the most precise predictors used in the assessment of potential future cardiovascular events. To facilitate the analysis of arterial wall thickening in serial clinical investigations, in this paper we have developed a novel fully automatic algorithm for the segmentation, measurement, and tracking of the intima media complex (IMC) in B-mode ultrasound video sequences. The proposed algorithm entails a two-stage image analysis process that initially addresses the segmentation of the IMC in the first frame of the ultrasound video sequence using a model-based approach; in the second step, a novel customized tracking procedure is applied to robustly detect the IMC in the subsequent frames. For the video tracking procedure, we introduce a spatially coherent algorithm called adaptive normalized correlation that prevents the tracking process from converging to wrong arterial interfaces. This represents the main contribution of this paper and was developed to deal with inconsistencies in the appearance of the IMC over the cardiac cycle. The quantitative evaluation has been carried out on 40 ultrasound video sequences of the common carotid artery (CCA) by comparing the results returned by the developed algorithm with respect to ground truth data that has been manually annotated by clinical experts. The measured IMTmean ± standard deviation recorded by the proposed algorithm is 0.60 mm ± 0.10, with a mean coefficient of variation (CV) of 2.05%, whereas the corresponding result obtained for the manually annotated ground truth data is 0.60 mm ± 0.11 with a mean CV equal to 5.60%. The numerical results reported in this paper indicate that the proposed algorithm is able to correctly segment and track the IMC in ultrasound CCA video sequences, and we were encouraged by the stability of our technique when applied to data captured under different imaging conditions. Future clinical studies will focus on the evaluation of patients that are affected by advanced cardiovascular conditions such as focal thickening and arterial plaques

    The Learning Tourism Destination: The potential of a learning organisation approach for improving the sustainability of tourism destinations

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    Globalisation, increasing complexity, and the need to address triple-bottom line sustainability has seen the proliferation of Learning Organisations (LO) who, by definition, have the capacity to anticipate environmental changes and economic opportunities and adapt accordingly. Such organisations use system dynamics modelling (SDM) for both strategic planning and the promotion of organisational learning. Although SDM has been applied in the context of tourism destination management for predictive reasons, the current literature does not analyse or recognise how this could be used as a foundation for an LO. This study introduces the concept of the Learning Tourism Destinations (LTD) and discusses, on the basis of a review of 6 case studies, the potential of SDM as a tool for the implementation and enhancement of collective learning processes. The results reveal that SDM is capable of promoting communication between stakeholders and stimulating organisational learning. It is suggested that the LTD approach be further utilised and explored

    Voluntary activation of muscle in humans: Does serotonergic neuromodulation matter?

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    Ionotropic inputs to motoneurones have the capacity to depolarise and hyperpolarise the motoneurone, whereas neuromodulatory inputs control the state of excitability of the motoneurone. Intracellular recordings of motoneurones from in vitro and in situ animal preparations have provided extraordinary insight into the mechanisms that underpin how neuromodulators regulate neuronal excitability. However, far fewer studies have attempted to translate the findings from cellular and molecular studies into a human model. In this review, we focus on the role that serotonin (5-HT) plays in muscle activation in humans. 5-HT is a potent regulator of neuronal firing rates, which can influence the force that can be generated by muscles during voluntary contractions. We firstly outline structural and functional characteristics of the serotonergic system, and then describe how motoneurone discharge can be facilitated and suppressed depending on the 5-HT receptor subtype that is activated. We then provide a narrative on how 5-HT effects can influence voluntary activation during muscle contractions in humans, and detail how 5-HT may be a mediator of exercise-induced fatigue that arises from the central nervous system. (Figure presented.)
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